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Light smokers (under 10 cigarettes per day): start at 3mg4mg Moderate smokers (1020 per day): start at 6mg8mg Heavy smokers (20+ per day): 8mg12mg is a reasonable starting point High-strength pouches (20mg50mg+): strictly for users with established high nicotine tolerance

Tobacco leaves were historically used for cultural, ceremonial, and spiritual purposes, and the domesticated species eventually spread with trade into Mesoamerica, the Caribbean, and later the United States

Over 30% of the world's population uses tobacco products, and 90% of that is from cigarettes

There has not been research on effective cessation strategies for vaping as there has been for smoking